Salk Institute

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Search Results - tumors

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Anti-Cancer Adenoviruses
Rapid Generation of Customized Tumor-Selective Oncolytic Adenoviruses Allows for the efficient optimization of viruses for use in oncolytic viral therapies. INVENTION: The goal of oncolytic viral therapy is to specifically infect and kill tumor cells without causing damage to normal cells. Although adenovirus is one of the most commonly used ...
Published: 4/9/2014   |   Inventor(s):  
Keywords(s): Adenovirus, Cancer Therapeutics, Cancer Vaccines, Oncology, Oncolytic Therapy, O'Shea, Personalized Medicine, Proliferative disorders, Synthetic Biology, Tumors, Vaccine, Viral Vectors, Virus
Category(s): Oncology
Adenoviral Tumor Diagnostics
Adenoviral Tumor Diagnostics Diagnostic viral reporters to define the malignant phenotype of tumors, and functionally determine their ability to respond to different therapies. INVENTION: Genome sequencing has accelerated our understanding of how molecular alterations determine a tumor's response to targeted drugs, ultimately leading to the ...
Published: 4/9/2014   |   Inventor(s):  
Keywords(s): Adenovirus, Cancer Diagnostics, Circulating Tumor Cells, Diagnostic, DNA Virus, Oncology, O'Shea, Personalized Medicine, Synthetic Biology, Tumors, Viral Reporters, Virus
Category(s): Diagnostics/Biomarkers, Oncology
FGF-2 Transcription Regulators: Diagnosis and Treatment of Cell Proliferative Disorders
FGF-2 Transcription Regulators: Diagnosis and Treatment of Cell Proliferative Disorders Invention is based on discovery of novel transcription factors that regulate fibroblast growth factor 2. INVENTION: Researchers at Salk have identified genes that encode polypeptides that are FGF-2 regulators of transcription (RFT). RFT-A is a negative regul...
Published: 8/2/2013   |   Inventor(s):  
Keywords(s): Alzheimer's Disease, Astrocytoma, Breast Cancer, Colon Cancer, Endometrial cancer, FGF, FGF-2, Gage, Glioblastoma, Glioma, Leukemia, Lung Cancer, Medulloblastoma, Melanoma, Neoplasia, Neoplastic Cell Proliferation, Neuroblastoma, Neurodegenerative Disorders, Oncology, Proliferative disorders, Prostate Cancer, Renal cancer, RFT, Screening methods, Testicular cancer, Tumors
Category(s): Drug Discovery, Oncology
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